Transcriptional regulation of plasminogen activator inhibitor type-1 mRNA in hep G2 cells by epidermal growth factor

Secretion of plasminogen activator inhibitor type-1 (PAI-1) by cultured cells is increased after exposure to specific cytokines and growth factors. We have shown previously that incubation of Hep G2 cells with epidermal growth factor (EGF) results in a marked increase in steady state levels of PAI-1...

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Veröffentlicht in:	Nucleic acids research 1991-01, Vol.19 (1), p.163-168
Hauptverfasser:	HOPKINS, W. E, WESTERHAUSEN, D. R, SOBEL, B. E, BILLADELLO, J. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cycloheximide - pharmacology Epidermal Growth Factor - physiology Fundamental and applied biological sciences. Psychology Gene Expression Regulation Glyceraldehyde-3-Phosphate Dehydrogenases - genetics Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism Half-Life Humans Kinetics Molecular and cellular biology Molecular genetics Plasminogen Inactivators - metabolism RNA, Messenger - biosynthesis RNA, Messenger - metabolism Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing Tumor Cells, Cultured
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