Sequence of a cDNA specifying subunit VIIc of human cytochrome c oxidase

Human cytochrome c oxidase (COX) is composed of 13 subunits, 3 of which are encoded by mitochondrial DNA, while 10 are encoded by nuclear DNA. UsinG cDNA specifying bovine COX subuNIt VIIc, we screened a human skeletaL muscle cDNA library in lambda gt10. The insert of the longest positive clone (pCO...

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Veröffentlicht in:	Nucleic acids research 1990-02, Vol.18 (3), p.684-684
Hauptverfasser:	KOGA, Y, FABRIZI, G. M, MITA, S, ARNAUDO, E, LOMAX, M. I, AQUA, M. S, GROSSMAN, L. I, SCHON, E. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biological and medical sciences Cattle DNA - genetics Electron Transport Complex IV - genetics Fundamental and applied biological sciences. Psychology genes Genes. Genome Humans Molecular and cellular biology Molecular genetics Molecular Sequence Data Muscles - analysis
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Beschreibung
Zusammenfassung:	Human cytochrome c oxidase (COX) is composed of 13 subunits, 3 of which are encoded by mitochondrial DNA, while 10 are encoded by nuclear DNA. UsinG cDNA specifying bovine COX subuNIt VIIc, we screened a human skeletaL muscle cDNA library in lambda gt10. The insert of the longest positive clone (pCOX7.183; sequence below) was 334 bp long, excluding the flanking EcoRI linkers and the 12-nt poly(A) tail. The deduced presequence of human subunit COX VIIc contains 16 amino acids, and is identical to that of bovine VIIc.
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/18.3.684