Experimental and clinical studies on diabetes mellitus evaluating the efficacy of an indigenous oral hypoglycaemic drug - arani (clerodendron phlomidis)

Diabetes mellitus is a common problem in clinical practice. An indigenous herbal drug Arani (Clerodendron phlomidis) was selected for this experimental and clinical study. The experimental study was conducted on albino rats. Arani inhibited the adrenaline induced hyperglycaemia effectively. The alcoholic extractive of Arani produced a well comparable fall in blood sugar to that of tolbutamide. Moreover, Arani caused a significant fall in hyperglycaemia ofalloxan diabetic patients along with clinical improvement. The results were found quite comparable to tolbutamide.