TSPY1 Copy Number Variation Influences Spermatogenesis and Shows Differences among Y Lineages

Context: TSPY1 is a tandemly-repeated gene on the human Y chromosome forming an array of approximately 21–35 copies. The testicular expression pattern and the inferred function of the TSPY1 protein suggest possible involvement in spermatogenesis. However, data are scarce on TSPY1 copy number variati...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2009-10, Vol.94 (10), p.4016-4022
Hauptverfasser:	Giachini, Claudia, Nuti, Francesca, Turner, Daniel J., Laface, Ilaria, Xue, Yali, Daguin, Fabrice, Forti, Gianni, Tyler-Smith, Chris, Krausz, Csilla
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Case-Control Studies Cell Cycle Proteins - genetics Chromosomes, Human, Y Endocrinopathies Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Humans Infertility, Male - genetics Italy Male Medical sciences Middle Aged Polymerase Chain Reaction Risk Factors Spermatogenesis - genetics Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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