Cell-to-cell variability in troponin I phosphorylation in a porcine model of pacing-induced heart failure

We tested the hypothesis that myocardial contractile protein phosphorylation and the Ca 2+ sensitivity of force production are dysregulated in a porcine model of pacing-induced heart failure (HF). The level of protein kinase A (PKA)-dependent cardiac troponin I (TnI) phosphorylation was lower in the...

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Veröffentlicht in:	Basic research in cardiology 2012-03, Vol.107 (2), p.244-244, Article 244
Hauptverfasser:	Czuriga, Dániel, Tóth, Attila, Pásztor, Enikő T., Balogh, Ágnes, Bodnár, Andrea, Nizsalóczki, Enikő, Lionetti, Vincenzo, Recchia, Fabio A., Czuriga, István, Édes, István, Papp, Zoltán
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cardiac Pacing, Artificial Cardiology Cell Separation Disease Models, Animal Flow Cytometry Heart Failure - metabolism Immunohistochemistry Male Medicine Medicine & Public Health Myofibrils - metabolism Original Contribution Phosphorylation Swine Troponin I - metabolism
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