Theory of Free Energy and Entropy in Noncovalent Binding

The theory of free energy and entropy in noncovalent binding is examined. Although it is a property of hte whole system, entropy has the capacity to be partitioned.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical reviews 2009-09, Vol.109 (9), p.4092-4107
Hauptverfasser: Zhou, Huan-Xiang, Gilson, Michael K
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 4107
container_issue 9
container_start_page 4092
container_title Chemical reviews
container_volume 109
creator Zhou, Huan-Xiang
Gilson, Michael K
description The theory of free energy and entropy in noncovalent binding is examined. Although it is a property of hte whole system, entropy has the capacity to be partitioned.
doi_str_mv 10.1021/cr800551w
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3329805</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67640483</sourcerecordid><originalsourceid>FETCH-LOGICAL-a496t-b1038d8ae9592c96383258b88f15bc9afb69cdd760d2974cf6fcdbbac3b4838c3</originalsourceid><addsrcrecordid>eNplkV1LwzAUhoMobn5c-AekCApeVJO0SZMbQcemwtCbeR3SNN06umQm7aT_3oyNzY-rc-A8vO97zgHgAsE7BDG6V45BSAj6OgB9RDCMKePwEPQhhDzGlJIeOPF-DtcQzo5BD3HCGCe8D9hkpq3rIltGI6d1NDTaTbtImiK0jbPLLqpM9GaNsitZa9NET5UpKjM9A0elrL0-39ZT8DEaTgYv8fj9-XXwOI5lymkT5wgmrGBSBzesOE1YggnLGSsRyRWXZU65KoqMwgLzLFUlLVWR51IlecoSppJT8LDRXbb5QhcqRHCyFktXLaTrhJWV-D0x1UxM7UokCeYMkiBwsxVw9rPVvhGLyitd19Jo23pBM5rC4BXAqz_g3LbOhOUExiklkLIsQLcbSDnrvdPlLgmCYv0MsXtGYC9_Rt-T2-sH4HoDSOX3Zv-FvgFGtJC4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>224650687</pqid></control><display><type>article</type><title>Theory of Free Energy and Entropy in Noncovalent Binding</title><source>ACS Publications</source><source>MEDLINE</source><creator>Zhou, Huan-Xiang ; Gilson, Michael K</creator><creatorcontrib>Zhou, Huan-Xiang ; Gilson, Michael K</creatorcontrib><description>The theory of free energy and entropy in noncovalent binding is examined. Although it is a property of hte whole system, entropy has the capacity to be partitioned.</description><identifier>ISSN: 0009-2665</identifier><identifier>EISSN: 1520-6890</identifier><identifier>DOI: 10.1021/cr800551w</identifier><identifier>PMID: 19588959</identifier><identifier>CODEN: CHREAY</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Binding sites ; Biochemistry ; Chemical bonds ; Entropy ; Molecular biology ; Protein Binding</subject><ispartof>Chemical reviews, 2009-09, Vol.109 (9), p.4092-4107</ispartof><rights>Copyright © 2009 American Chemical Society</rights><rights>Copyright American Chemical Society Sep 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a496t-b1038d8ae9592c96383258b88f15bc9afb69cdd760d2974cf6fcdbbac3b4838c3</citedby><cites>FETCH-LOGICAL-a496t-b1038d8ae9592c96383258b88f15bc9afb69cdd760d2974cf6fcdbbac3b4838c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/cr800551w$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/cr800551w$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>230,314,776,780,881,2752,27053,27901,27902,56713,56763</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19588959$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhou, Huan-Xiang</creatorcontrib><creatorcontrib>Gilson, Michael K</creatorcontrib><title>Theory of Free Energy and Entropy in Noncovalent Binding</title><title>Chemical reviews</title><addtitle>Chem. Rev</addtitle><description>The theory of free energy and entropy in noncovalent binding is examined. Although it is a property of hte whole system, entropy has the capacity to be partitioned.</description><subject>Binding sites</subject><subject>Biochemistry</subject><subject>Chemical bonds</subject><subject>Entropy</subject><subject>Molecular biology</subject><subject>Protein Binding</subject><issn>0009-2665</issn><issn>1520-6890</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkV1LwzAUhoMobn5c-AekCApeVJO0SZMbQcemwtCbeR3SNN06umQm7aT_3oyNzY-rc-A8vO97zgHgAsE7BDG6V45BSAj6OgB9RDCMKePwEPQhhDzGlJIeOPF-DtcQzo5BD3HCGCe8D9hkpq3rIltGI6d1NDTaTbtImiK0jbPLLqpM9GaNsitZa9NET5UpKjM9A0elrL0-39ZT8DEaTgYv8fj9-XXwOI5lymkT5wgmrGBSBzesOE1YggnLGSsRyRWXZU65KoqMwgLzLFUlLVWR51IlecoSppJT8LDRXbb5QhcqRHCyFktXLaTrhJWV-D0x1UxM7UokCeYMkiBwsxVw9rPVvhGLyitd19Jo23pBM5rC4BXAqz_g3LbOhOUExiklkLIsQLcbSDnrvdPlLgmCYv0MsXtGYC9_Rt-T2-sH4HoDSOX3Zv-FvgFGtJC4</recordid><startdate>20090901</startdate><enddate>20090901</enddate><creator>Zhou, Huan-Xiang</creator><creator>Gilson, Michael K</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20090901</creationdate><title>Theory of Free Energy and Entropy in Noncovalent Binding</title><author>Zhou, Huan-Xiang ; Gilson, Michael K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a496t-b1038d8ae9592c96383258b88f15bc9afb69cdd760d2974cf6fcdbbac3b4838c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Binding sites</topic><topic>Biochemistry</topic><topic>Chemical bonds</topic><topic>Entropy</topic><topic>Molecular biology</topic><topic>Protein Binding</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhou, Huan-Xiang</creatorcontrib><creatorcontrib>Gilson, Michael K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chemical reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhou, Huan-Xiang</au><au>Gilson, Michael K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Theory of Free Energy and Entropy in Noncovalent Binding</atitle><jtitle>Chemical reviews</jtitle><addtitle>Chem. Rev</addtitle><date>2009-09-01</date><risdate>2009</risdate><volume>109</volume><issue>9</issue><spage>4092</spage><epage>4107</epage><pages>4092-4107</pages><issn>0009-2665</issn><eissn>1520-6890</eissn><coden>CHREAY</coden><abstract>The theory of free energy and entropy in noncovalent binding is examined. Although it is a property of hte whole system, entropy has the capacity to be partitioned.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>19588959</pmid><doi>10.1021/cr800551w</doi><tpages>16</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0009-2665
ispartof Chemical reviews, 2009-09, Vol.109 (9), p.4092-4107
issn 0009-2665
1520-6890
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3329805
source ACS Publications; MEDLINE
subjects Binding sites
Biochemistry
Chemical bonds
Entropy
Molecular biology
Protein Binding
title Theory of Free Energy and Entropy in Noncovalent Binding
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T21%3A52%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Theory%20of%20Free%20Energy%20and%20Entropy%20in%20Noncovalent%20Binding&rft.jtitle=Chemical%20reviews&rft.au=Zhou,%20Huan-Xiang&rft.date=2009-09-01&rft.volume=109&rft.issue=9&rft.spage=4092&rft.epage=4107&rft.pages=4092-4107&rft.issn=0009-2665&rft.eissn=1520-6890&rft.coden=CHREAY&rft_id=info:doi/10.1021/cr800551w&rft_dat=%3Cproquest_pubme%3E67640483%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=224650687&rft_id=info:pmid/19588959&rfr_iscdi=true