The Inhibition of Ureteral Motility by Periureteral Adipose Tissue

Perivascular adipose tissue exerts an anticontractile influence on vascular smooth muscle. This study was conducted to determine whether periureteral adipose tissue (PUAT) could exert a similar influence upon ureteral smooth muscle. Acetylcholine-stimulated (10−7 M–10−4 M) contractile responses of u...

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Veröffentlicht in:ISRN urology 2012, Vol.2012 (2012), p.1-7
Hauptverfasser: Killian, Lyndsey M., Bund, Stuart J.
Format: Artikel
Sprache:eng
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Zusammenfassung:Perivascular adipose tissue exerts an anticontractile influence on vascular smooth muscle. This study was conducted to determine whether periureteral adipose tissue (PUAT) could exert a similar influence upon ureteral smooth muscle. Acetylcholine-stimulated (10−7 M–10−4 M) contractile responses of ureteral segments obtained from male Wistar rats were recorded in the presence and absence of PUAT. Ureters with PUAT generated phasic contractile responses with significantly lower frequencies (P
ISSN:2090-5807
2090-5815
2090-5815
DOI:10.5402/2012/312487