Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation

RNAa (RNA activation) is a mechanism by which small dsRNA (double-stranded RNA), termed saRNA (small activating RNA), target promoter sequences to induce gene expression. This technique represents a novel approach to gene overexpression without the use of exogenous DNA. In the present study, we inve...

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Veröffentlicht in:Biochemical journal 2012-05, Vol.443 (3), p.821-828
Hauptverfasser: Wang, Xiaoling, Wang, Ji, Huang, Vera, Place, Robert F, Li, Long-Cheng
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Sprache:eng
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