Intravascular recovery of VWF and FVIII following intraperitoneal injection and differences from intravenous and subcutaneous injection in mice

Intravenous infusion studies in humans suggest that both von Willebrand factor (VWF) and factor VIII (FVIII) remain intravascular in contrast to other coagulation proteins. We explored whether infusion of VWF and FVIII by either intraperitoneal (i.p.) or subcutaneous (s.c.) injection would result in...

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Veröffentlicht in:	Haemophilia : the official journal of the World Federation of Hemophilia 2012-07, Vol.18 (4), p.639-646
Hauptverfasser:	SHI, Q., KUETHER, E. L., SCHROEDER, J. A., FAHS, S. A., MONTGOMERY, R. R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals factor VIII Factor VIII - administration & dosage Factor VIII - pharmacokinetics Infusion Injections, Intraperitoneal Injections, Intravenous Injections, Subcutaneous Intraperitoneal Mice Mice, Inbred C57BL von Willebrand factor von Willebrand Factor - administration & dosage von Willebrand Factor - pharmacokinetics
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