Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis

BackgroundInflammatory bowel diseases, encompassing Crohn's disease and ulcerative colitis, are characterised by persistent leucocyte tissue infiltration leading to perpetuation of an inappropriate inflammatory cascade. The neuronal guidance molecule netrin-1 has recently been implicated in the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Gut 2012-05, Vol.61 (5), p.695-705
Hauptverfasser:	Aherne, Carol M, Collins, Colm B, Masterson, Joanne C, Tizzano, Marco, Boyle, Theresa A, Westrich, Joseph A, Parnes, Jason A, Furuta, Glenn T, Rivera-Nieves, Jesús, Eltzschig, Holger K
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Apoptosis Biological and medical sciences Biomarkers - metabolism Cell Line Colitis - immunology Colitis - metabolism Colon Disease Models, Animal epithelial permeability Gastroenterology. Liver. Pancreas. Abdomen Inflammation Inflammatory Bowel Disease Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - metabolism inflammatory cells Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Leukocytes Medical sciences Mice Mice, Inbred C57BL mucosal immunology Nerve Growth Factors - administration & dosage Nerve Growth Factors - metabolism Netrin-1 Neutrophil Infiltration Neutrophils Permeability Recruitment Rodents Studies Transendothelial and Transepithelial Migration Tumor necrosis factor-TNF Tumor Suppressor Proteins - administration & dosage Tumor Suppressor Proteins - metabolism Ulcerative colitis Variance analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!