Promyelocytic Leukemia Protein in Retinoic Acid‐Induced Chromatin Remodeling of Oct4 Gene Promoter

Promyelocytic leukemia (Pml) protein is required for Oct4 gene expression and the maintenance of its open chromatin conformation in stem cells. In proliferating stem cells, Pml‐nuclear body, along with transcription factors TR2, steroidogenic factor 1 (SF1) and Sp1, and Brg1‐dependent chromatin remo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2011-04, Vol.29 (4), p.660-669
Hauptverfasser:	Chuang, Ya‐Shan, Huang, Wei‐Hong, Park, Sung Wook, Persaud, Shawna D., Hung, Chen‐Hsiang, Ho, Ping‐Chih, Wei, Li‐Na
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - genetics Chromatin Assembly and Disassembly - genetics Chromatin Immunoprecipitation Chromatin remodeling Embryonic stem cells Gene Expression Regulation, Developmental Intracellular Signaling Peptides and Proteins - metabolism Mice Nuclear Proteins - biosynthesis Nuclear Proteins - metabolism Nucleosomes Oct4 Octamer Transcription Factor-3 - genetics P19 Pml‐NB Promoter Regions, Genetic Promyelocytic Leukemia Protein Retinoic acid Reverse Transcriptase Polymerase Chain Reaction RNA Interference RNA, Small Interfering Sp1 Transcription Factor - metabolism Steroidogenic Factor 1 - metabolism TR2 Transcription Factors - biosynthesis Transcription Factors - metabolism Tretinoin - metabolism Tumor Suppressor Proteins - biosynthesis Tumor Suppressor Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!