Spinal Cord Tolerance to Reirradiation With Single-Fraction Radiosurgery: A Swine Model

Purpose This study was performed to determine swine spinal cord tolerance to single-fraction, partial-volume irradiation 1 year after receiving uniform irradiation to 30 Gy in 10 fractions. Methods and Materials A 10-cm length of spinal cord (C3–T1) was uniformly irradiated to 30 Gy in 10 consecutiv...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2012-07, Vol.83 (3), p.1031-1037
Hauptverfasser:	Medin, Paul M., Ph.D, Foster, Ryan D., Ph.D, van der Kogel, Albert J., Ph.D, Sayre, James W., Ph.D, McBride, William H., D.Sc, Solberg, Timothy D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cervical Vertebrae Diseases of the nervous system Dose-Response Relationship, Radiation Female Gait Disorders, Neurologic - etiology HAZARDS Hematology, Oncology and Palliative Medicine HISTOLOGY IRRADIATION Medical sciences Myelin Sheath - pathology Myelin Sheath - radiation effects NECROSIS Radiation Dosage RADIATION DOSE DISTRIBUTIONS RADIATION DOSES RADIATION INJURIES Radiation Injuries, Experimental - complications Radiation Injuries, Experimental - pathology Radiation therapy and radiosensitizing agent Radiation Tolerance Radiology RADIOLOGY AND NUCLEAR MEDICINE Radiosurgery - adverse effects Radiosurgery - methods RADIOTHERAPY Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Reirradiation Retreatment SPINAL CORD Spinal Cord - pathology Spinal Cord - radiation effects Spinal cord tolerance Stereotactic spinal radiosurgery SURGERY SWINE Swine, Miniature Time Factors Treatment with physical agents Treatment. General aspects Tumors
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