Nucleotide sequence of a cDNA encoding ammodytin L

Ammodytin L is a very basic phospholipase A sub(2) homologue isolated from European viper (Vipera ammodytes)) venom as the fraction 1. A cDNA coding for ammodytin L was found by screening a venom gland cDNA library with a mixed oligonucleotide probe deduced from the part of a highly conserved region...

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Veröffentlicht in:Nucleic acids research 1990-08, Vol.18 (15), p.4601-4601
Hauptverfasser: PUNGERCAR, J, NINGSHENG LIANG, STRUKELJ, B, GUBENSEK, F
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creator PUNGERCAR, J
NINGSHENG LIANG
STRUKELJ, B
GUBENSEK, F
description Ammodytin L is a very basic phospholipase A sub(2) homologue isolated from European viper (Vipera ammodytes)) venom as the fraction 1. A cDNA coding for ammodytin L was found by screening a venom gland cDNA library with a mixed oligonucleotide probe deduced from the part of a highly conserved region responsible for calcium binding found in most phospholipase A sub(2). It codes for a 122 amino acid residue mature protein, preceded by a 16 residue signal peptide. Ammodytin L cDNA shows about 90% nucleotide and 74% amino acid similarity to ammodytoxins C and B.
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subjects Amino Acid Sequence
Base Sequence
Biological and medical sciences
DNA - genetics
Fundamental and applied biological sciences. Psychology
genes
Genes. Genome
Molecular and cellular biology
Molecular genetics
Molecular Sequence Data
phospholipase A2
Phospholipases - genetics
Phospholipases A - genetics
Sequence Homology, Nucleic Acid
venom
Viper Venoms - analysis
Viper Venoms - genetics
Vipera ammodytes
title Nucleotide sequence of a cDNA encoding ammodytin L
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