Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect

Brassica vegetables are attracting a great deal of attention as healthy foods because of the fact that they contain substantial amounts of secondary metabolite glucosinolates that are converted into isothiocyanates, such as sulforaphane [(−)1-isothiocyanato-4 R -(methylsulfinyl)-butane] ( R -SFN), t...

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Veröffentlicht in:AGE 2012-04, Vol.34 (2), p.281-293
Hauptverfasser: Zanichelli, Fulvia, Capasso, Stefania, Cipollaro, Marilena, Pagnotta, Eleonora, Cartenì, Maria, Casale, Fiorina, Iori, Renato, Galderisi, Umberto
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Sprache:eng
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