New roles for renin and prorenin in heart failure and cardiorenal crosstalk

The renin-angiotensin-aldosterone-system (RAAS) plays a central role in the pathophysiology of heart failure and cardiorenal interaction. Drugs interfering in the RAAS form the pillars in treatment of heart failure and cardiorenal syndrome. Although RAAS inhibitors improve prognosis, heart failure–a...

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Veröffentlicht in:	Heart failure reviews 2012-03, Vol.17 (2), p.191-201
Hauptverfasser:	Schroten, Nicolas F., Gaillard, Carlo A. J. M., van Veldhuisen, Dirk J., Szymanski, Mariusz K., Hillege, Hans L., de Boer, Rudolf A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - therapeutic use Antihypertensive Agents - therapeutic use Cardio-Renal Syndrome - physiopathology Cardiology Fumarates - therapeutic use Heart Failure - blood Heart Failure - drug therapy Heart Failure - physiopathology Humans Medicine Medicine & Public Health Renin - antagonists & inhibitors Renin - physiology Renin-Angiotensin System - drug effects Renin-Angiotensin System - physiology
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