MASP-2 activation is involved in ischemia-related necrotic myocardial injury in humans

Abstract Background/objectives Insufficient blood supply to the heart results in ischemic injury manifested clinically as myocardial infarction (MI). Following ischemia, inflammation is provoked and related to the clinical outcomes. A recent basic science study indicates that complement factor MASP-...

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Veröffentlicht in:	International journal of cardiology 2013-06, Vol.166 (2), p.499-504
Hauptverfasser:	Zhang, Ming, Hou, Yunfang Joan, Cavusoglu, Erdal, Lee, Daniel C, Steffensen, Rudi, Yang, Liming, Bashari, Daniel, Villamil, Jose, Moussa, Motaz, Fernaine, George, Jensenius, Jens C, Marmur, Jonathan D, Ko, Wilson, Shevde, Ketan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers - blood Cardiology. Vascular system Cardiovascular Coronary heart disease Enzyme Activation - physiology Female Heart Humans Male Mannose-Binding Protein-Associated Serine Proteases - metabolism MASP-2 Medical sciences Middle Aged Myocardial ischemia Myocardial Ischemia - blood Myocardial Ischemia - diagnosis Myocardial Ischemia - enzymology Myocarditis. Cardiomyopathies Myocardium - enzymology Myocardium - pathology Necrosis Young Adult
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