Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China
Abstract Background China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their...
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| Veröffentlicht in: | Journal of affective disorders 2011-05, Vol.130 (3), p.421-428 |
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| creator | Atkinson, J. Hampton Jin, Hua Shi, Chuan Yu, Xin Duarte, Nichole A Casey, Corinna Young Franklin, Donald R Vigil, Ofilio Cysique, Lucette Wolfson, Tanya Riggs, P. Katie Gupta, Saurabh Letendre, Scott Marcotte, Thomas D Grant, Igor Wu, Zunyou Heaton, Robert K |
| description | Abstract Background China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality. Methods HIV-infected (HIV+) former plasma donors (N = 203) and HIV-negative (HIV−) donor controls (N = 198) completed the World Mental Health Survey Composite International Diagnostic Interview to determine lifetime major depressive disorder (MDD), substance use disorders, and suicidality. Current mood and suicidality were assessed with the Beck Depression Inventory-II. Everyday function was measured by an Activity of Daily Living questionnaire; life quality was evaluated by the Medical Outcomes Study — HIV. Results HIV+ participants had known their infected status for 2 years on average. Most were taking antiretroviral treatment and had frank AIDS. Rates of current MDD were similar across groups (1–2%), but HIV+ had a higher frequency of lifetime MDD (14% vs. 5%, p < .05). Its onset preceded date of known infection in one-third of cases. Alcoholism was the only substance use disorder detected; HIV+ had a higher proportion of lifetime substance use diagnoses (14% vs. 6%, p < .05). Depression and AIDS independently predicted worse daily functioning and life quality, and unemployment. Limitations The epicenter of China HIV has moved into urban injection drug users, limiting the representativeness of this sample. Conclusions High rates of MDD and its impact suggest that in China, as elsewhere, comprehensive care requires detection and treatment of mood disorder. |
| doi_str_mv | 10.1016/j.jad.2010.10.039 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3307799</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0165032710006683</els_id><sourcerecordid>881448123</sourcerecordid><originalsourceid>FETCH-LOGICAL-c599t-4f3ebe48840d5d98b3413c3e7a354794f0fddc937b8664000f7aadfc8fc32b1a3</originalsourceid><addsrcrecordid>eNqFkkuLFDEQgBtR3HH1B3iRXMRTj3l1J0FYkEHdhQUFH9eQzmMmbXcyJt2L8-9N74zr46CnkOSrSlW-qqqnCK4RRO3Lft0rs8bwdr-GRNyrVqhhpMYNYverVWGaGhLMzqpHOfcQwlYw-LA6wwgK2hC4qrYf8kHvvJqS10DHMNnvE4gOXM6jCuBqHOcQjXVeexv0AXzxac7AB2f15GMAaoxhC1xMo01gP6g8KmBiiGmBQJqTGsBm54N6XD1wasj2yWk9rz6_ffNpc1lfv393tXl9XetGiKmmjtjOUs4pNI0RvCMUEU0sU6ShTFAHnTFaENbxtqWlIceUMk5zpwnukCLn1cUx737uRmu0DVOpQe6TH1U6yKi8_PMm-J3cxhtJCGRMiJLgxSlBit9mmyc5-qztMKhg45ylgJhQLBD7L8k5opQjTAqJjqROMedk3V09CMrFpOxlMSkXk8tRMVlinv3eyF3ET3UFeH4CVNZqcEkF7fMvjiLGeIML9-rI2fLtN94mmW9lWuNTsShN9P8s4-KvaD344MuDX-3B5j7OKRSfEsmMJZQfl5FbJg4tw9ZyQn4AETLSjw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>881448123</pqid></control><display><type>article</type><title>Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China</title><source>MEDLINE</source><source>Applied Social Sciences Index & Abstracts (ASSIA)</source><source>Access via ScienceDirect (Elsevier)</source><creator>Atkinson, J. Hampton ; Jin, Hua ; Shi, Chuan ; Yu, Xin ; Duarte, Nichole A ; Casey, Corinna Young ; Franklin, Donald R ; Vigil, Ofilio ; Cysique, Lucette ; Wolfson, Tanya ; Riggs, P. Katie ; Gupta, Saurabh ; Letendre, Scott ; Marcotte, Thomas D ; Grant, Igor ; Wu, Zunyou ; Heaton, Robert K</creator><creatorcontrib>Atkinson, J. Hampton ; Jin, Hua ; Shi, Chuan ; Yu, Xin ; Duarte, Nichole A ; Casey, Corinna Young ; Franklin, Donald R ; Vigil, Ofilio ; Cysique, Lucette ; Wolfson, Tanya ; Riggs, P. Katie ; Gupta, Saurabh ; Letendre, Scott ; Marcotte, Thomas D ; Grant, Igor ; Wu, Zunyou ; Heaton, Robert K ; the HIV Neurobehavioral Research Center Group ; HIV Neurobehavioral Research Center Group</creatorcontrib><description>Abstract Background China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality. Methods HIV-infected (HIV+) former plasma donors (N = 203) and HIV-negative (HIV−) donor controls (N = 198) completed the World Mental Health Survey Composite International Diagnostic Interview to determine lifetime major depressive disorder (MDD), substance use disorders, and suicidality. Current mood and suicidality were assessed with the Beck Depression Inventory-II. Everyday function was measured by an Activity of Daily Living questionnaire; life quality was evaluated by the Medical Outcomes Study — HIV. Results HIV+ participants had known their infected status for 2 years on average. Most were taking antiretroviral treatment and had frank AIDS. Rates of current MDD were similar across groups (1–2%), but HIV+ had a higher frequency of lifetime MDD (14% vs. 5%, p < .05). Its onset preceded date of known infection in one-third of cases. Alcoholism was the only substance use disorder detected; HIV+ had a higher proportion of lifetime substance use diagnoses (14% vs. 6%, p < .05). Depression and AIDS independently predicted worse daily functioning and life quality, and unemployment. Limitations The epicenter of China HIV has moved into urban injection drug users, limiting the representativeness of this sample. Conclusions High rates of MDD and its impact suggest that in China, as elsewhere, comprehensive care requires detection and treatment of mood disorder.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2010.10.039</identifier><identifier>PMID: 21094530</identifier><identifier>CODEN: JADID7</identifier><language>eng</language><publisher>Oxford: Elsevier B.V</publisher><subject>Acquired immune deficiency syndrome ; Activities of daily living ; Adolescent ; Adult ; Adult and adolescent clinical studies ; Affective disorders ; AIDS ; Alcoholism ; Antiviral agents ; Biological and medical sciences ; Blood Donors - psychology ; Case-Control Studies ; China ; China - epidemiology ; Depression ; Depressive Disorder, Major - epidemiology ; Depressive Disorder, Major - psychology ; Depressive personality disorders ; Donors ; Drug abuse ; Epidemics ; Female ; HIV ; HIV Infections - psychology ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Infection ; Infectious diseases ; Inventories ; Male ; Medical sciences ; Mental disorders ; Middle Aged ; Mood ; Mood disorders ; Psychiatric Status Rating Scales ; Psychiatry ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Public health ; Risk Factors ; Rural Population - statistics & numerical data ; Substance abuse disorders ; Substance-Related Disorders - epidemiology ; Substance-Related Disorders - psychology ; Suicide ; Suicide - psychology ; Suicide - statistics & numerical data ; Surveys and Questionnaires ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Young Adult</subject><ispartof>Journal of affective disorders, 2011-05, Vol.130 (3), p.421-428</ispartof><rights>2010</rights><rights>2015 INIST-CNRS</rights><rights>Published by Elsevier B.V.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c599t-4f3ebe48840d5d98b3413c3e7a354794f0fddc937b8664000f7aadfc8fc32b1a3</citedby><cites>FETCH-LOGICAL-c599t-4f3ebe48840d5d98b3413c3e7a354794f0fddc937b8664000f7aadfc8fc32b1a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jad.2010.10.039$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,315,781,785,886,3551,27929,27930,31005,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24177852$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21094530$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Atkinson, J. Hampton</creatorcontrib><creatorcontrib>Jin, Hua</creatorcontrib><creatorcontrib>Shi, Chuan</creatorcontrib><creatorcontrib>Yu, Xin</creatorcontrib><creatorcontrib>Duarte, Nichole A</creatorcontrib><creatorcontrib>Casey, Corinna Young</creatorcontrib><creatorcontrib>Franklin, Donald R</creatorcontrib><creatorcontrib>Vigil, Ofilio</creatorcontrib><creatorcontrib>Cysique, Lucette</creatorcontrib><creatorcontrib>Wolfson, Tanya</creatorcontrib><creatorcontrib>Riggs, P. Katie</creatorcontrib><creatorcontrib>Gupta, Saurabh</creatorcontrib><creatorcontrib>Letendre, Scott</creatorcontrib><creatorcontrib>Marcotte, Thomas D</creatorcontrib><creatorcontrib>Grant, Igor</creatorcontrib><creatorcontrib>Wu, Zunyou</creatorcontrib><creatorcontrib>Heaton, Robert K</creatorcontrib><creatorcontrib>the HIV Neurobehavioral Research Center Group</creatorcontrib><creatorcontrib>HIV Neurobehavioral Research Center Group</creatorcontrib><title>Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>Abstract Background China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality. Methods HIV-infected (HIV+) former plasma donors (N = 203) and HIV-negative (HIV−) donor controls (N = 198) completed the World Mental Health Survey Composite International Diagnostic Interview to determine lifetime major depressive disorder (MDD), substance use disorders, and suicidality. Current mood and suicidality were assessed with the Beck Depression Inventory-II. Everyday function was measured by an Activity of Daily Living questionnaire; life quality was evaluated by the Medical Outcomes Study — HIV. Results HIV+ participants had known their infected status for 2 years on average. Most were taking antiretroviral treatment and had frank AIDS. Rates of current MDD were similar across groups (1–2%), but HIV+ had a higher frequency of lifetime MDD (14% vs. 5%, p < .05). Its onset preceded date of known infection in one-third of cases. Alcoholism was the only substance use disorder detected; HIV+ had a higher proportion of lifetime substance use diagnoses (14% vs. 6%, p < .05). Depression and AIDS independently predicted worse daily functioning and life quality, and unemployment. Limitations The epicenter of China HIV has moved into urban injection drug users, limiting the representativeness of this sample. Conclusions High rates of MDD and its impact suggest that in China, as elsewhere, comprehensive care requires detection and treatment of mood disorder.</description><subject>Acquired immune deficiency syndrome</subject><subject>Activities of daily living</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Affective disorders</subject><subject>AIDS</subject><subject>Alcoholism</subject><subject>Antiviral agents</subject><subject>Biological and medical sciences</subject><subject>Blood Donors - psychology</subject><subject>Case-Control Studies</subject><subject>China</subject><subject>China - epidemiology</subject><subject>Depression</subject><subject>Depressive Disorder, Major - epidemiology</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Depressive personality disorders</subject><subject>Donors</subject><subject>Drug abuse</subject><subject>Epidemics</subject><subject>Female</subject><subject>HIV</subject><subject>HIV Infections - psychology</subject><subject>Human immunodeficiency virus</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infection</subject><subject>Infectious diseases</subject><subject>Inventories</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental disorders</subject><subject>Middle Aged</subject><subject>Mood</subject><subject>Mood disorders</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Public health</subject><subject>Risk Factors</subject><subject>Rural Population - statistics & numerical data</subject><subject>Substance abuse disorders</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Substance-Related Disorders - psychology</subject><subject>Suicide</subject><subject>Suicide - psychology</subject><subject>Suicide - statistics & numerical data</subject><subject>Surveys and Questionnaires</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><subject>Young Adult</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqFkkuLFDEQgBtR3HH1B3iRXMRTj3l1J0FYkEHdhQUFH9eQzmMmbXcyJt2L8-9N74zr46CnkOSrSlW-qqqnCK4RRO3Lft0rs8bwdr-GRNyrVqhhpMYNYverVWGaGhLMzqpHOfcQwlYw-LA6wwgK2hC4qrYf8kHvvJqS10DHMNnvE4gOXM6jCuBqHOcQjXVeexv0AXzxac7AB2f15GMAaoxhC1xMo01gP6g8KmBiiGmBQJqTGsBm54N6XD1wasj2yWk9rz6_ffNpc1lfv393tXl9XetGiKmmjtjOUs4pNI0RvCMUEU0sU6ShTFAHnTFaENbxtqWlIceUMk5zpwnukCLn1cUx737uRmu0DVOpQe6TH1U6yKi8_PMm-J3cxhtJCGRMiJLgxSlBit9mmyc5-qztMKhg45ylgJhQLBD7L8k5opQjTAqJjqROMedk3V09CMrFpOxlMSkXk8tRMVlinv3eyF3ET3UFeH4CVNZqcEkF7fMvjiLGeIML9-rI2fLtN94mmW9lWuNTsShN9P8s4-KvaD344MuDX-3B5j7OKRSfEsmMJZQfl5FbJg4tw9ZyQn4AETLSjw</recordid><startdate>20110501</startdate><enddate>20110501</enddate><creator>Atkinson, J. Hampton</creator><creator>Jin, Hua</creator><creator>Shi, Chuan</creator><creator>Yu, Xin</creator><creator>Duarte, Nichole A</creator><creator>Casey, Corinna Young</creator><creator>Franklin, Donald R</creator><creator>Vigil, Ofilio</creator><creator>Cysique, Lucette</creator><creator>Wolfson, Tanya</creator><creator>Riggs, P. Katie</creator><creator>Gupta, Saurabh</creator><creator>Letendre, Scott</creator><creator>Marcotte, Thomas D</creator><creator>Grant, Igor</creator><creator>Wu, Zunyou</creator><creator>Heaton, Robert K</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>20110501</creationdate><title>Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China</title><author>Atkinson, J. Hampton ; Jin, Hua ; Shi, Chuan ; Yu, Xin ; Duarte, Nichole A ; Casey, Corinna Young ; Franklin, Donald R ; Vigil, Ofilio ; Cysique, Lucette ; Wolfson, Tanya ; Riggs, P. Katie ; Gupta, Saurabh ; Letendre, Scott ; Marcotte, Thomas D ; Grant, Igor ; Wu, Zunyou ; Heaton, Robert K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c599t-4f3ebe48840d5d98b3413c3e7a354794f0fddc937b8664000f7aadfc8fc32b1a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Activities of daily living</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Affective disorders</topic><topic>AIDS</topic><topic>Alcoholism</topic><topic>Antiviral agents</topic><topic>Biological and medical sciences</topic><topic>Blood Donors - psychology</topic><topic>Case-Control Studies</topic><topic>China</topic><topic>China - epidemiology</topic><topic>Depression</topic><topic>Depressive Disorder, Major - epidemiology</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Depressive personality disorders</topic><topic>Donors</topic><topic>Drug abuse</topic><topic>Epidemics</topic><topic>Female</topic><topic>HIV</topic><topic>HIV Infections - psychology</topic><topic>Human immunodeficiency virus</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Infection</topic><topic>Infectious diseases</topic><topic>Inventories</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental disorders</topic><topic>Middle Aged</topic><topic>Mood</topic><topic>Mood disorders</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Public health</topic><topic>Risk Factors</topic><topic>Rural Population - statistics & numerical data</topic><topic>Substance abuse disorders</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Substance-Related Disorders - psychology</topic><topic>Suicide</topic><topic>Suicide - psychology</topic><topic>Suicide - statistics & numerical data</topic><topic>Surveys and Questionnaires</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Atkinson, J. Hampton</creatorcontrib><creatorcontrib>Jin, Hua</creatorcontrib><creatorcontrib>Shi, Chuan</creatorcontrib><creatorcontrib>Yu, Xin</creatorcontrib><creatorcontrib>Duarte, Nichole A</creatorcontrib><creatorcontrib>Casey, Corinna Young</creatorcontrib><creatorcontrib>Franklin, Donald R</creatorcontrib><creatorcontrib>Vigil, Ofilio</creatorcontrib><creatorcontrib>Cysique, Lucette</creatorcontrib><creatorcontrib>Wolfson, Tanya</creatorcontrib><creatorcontrib>Riggs, P. Katie</creatorcontrib><creatorcontrib>Gupta, Saurabh</creatorcontrib><creatorcontrib>Letendre, Scott</creatorcontrib><creatorcontrib>Marcotte, Thomas D</creatorcontrib><creatorcontrib>Grant, Igor</creatorcontrib><creatorcontrib>Wu, Zunyou</creatorcontrib><creatorcontrib>Heaton, Robert K</creatorcontrib><creatorcontrib>the HIV Neurobehavioral Research Center Group</creatorcontrib><creatorcontrib>HIV Neurobehavioral Research Center Group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Atkinson, J. Hampton</au><au>Jin, Hua</au><au>Shi, Chuan</au><au>Yu, Xin</au><au>Duarte, Nichole A</au><au>Casey, Corinna Young</au><au>Franklin, Donald R</au><au>Vigil, Ofilio</au><au>Cysique, Lucette</au><au>Wolfson, Tanya</au><au>Riggs, P. Katie</au><au>Gupta, Saurabh</au><au>Letendre, Scott</au><au>Marcotte, Thomas D</au><au>Grant, Igor</au><au>Wu, Zunyou</au><au>Heaton, Robert K</au><aucorp>the HIV Neurobehavioral Research Center Group</aucorp><aucorp>HIV Neurobehavioral Research Center Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2011-05-01</date><risdate>2011</risdate><volume>130</volume><issue>3</issue><spage>421</spage><epage>428</epage><pages>421-428</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><coden>JADID7</coden><abstract>Abstract Background China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality. Methods HIV-infected (HIV+) former plasma donors (N = 203) and HIV-negative (HIV−) donor controls (N = 198) completed the World Mental Health Survey Composite International Diagnostic Interview to determine lifetime major depressive disorder (MDD), substance use disorders, and suicidality. Current mood and suicidality were assessed with the Beck Depression Inventory-II. Everyday function was measured by an Activity of Daily Living questionnaire; life quality was evaluated by the Medical Outcomes Study — HIV. Results HIV+ participants had known their infected status for 2 years on average. Most were taking antiretroviral treatment and had frank AIDS. Rates of current MDD were similar across groups (1–2%), but HIV+ had a higher frequency of lifetime MDD (14% vs. 5%, p < .05). Its onset preceded date of known infection in one-third of cases. Alcoholism was the only substance use disorder detected; HIV+ had a higher proportion of lifetime substance use diagnoses (14% vs. 6%, p < .05). Depression and AIDS independently predicted worse daily functioning and life quality, and unemployment. Limitations The epicenter of China HIV has moved into urban injection drug users, limiting the representativeness of this sample. Conclusions High rates of MDD and its impact suggest that in China, as elsewhere, comprehensive care requires detection and treatment of mood disorder.</abstract><cop>Oxford</cop><pub>Elsevier B.V</pub><pmid>21094530</pmid><doi>10.1016/j.jad.2010.10.039</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of affective disorders, 2011-05, Vol.130 (3), p.421-428 |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Access via ScienceDirect (Elsevier) |
| subjects | Acquired immune deficiency syndrome Activities of daily living Adolescent Adult Adult and adolescent clinical studies Affective disorders AIDS Alcoholism Antiviral agents Biological and medical sciences Blood Donors - psychology Case-Control Studies China China - epidemiology Depression Depressive Disorder, Major - epidemiology Depressive Disorder, Major - psychology Depressive personality disorders Donors Drug abuse Epidemics Female HIV HIV Infections - psychology Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infection Infectious diseases Inventories Male Medical sciences Mental disorders Middle Aged Mood Mood disorders Psychiatric Status Rating Scales Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Public health Risk Factors Rural Population - statistics & numerical data Substance abuse disorders Substance-Related Disorders - epidemiology Substance-Related Disorders - psychology Suicide Suicide - psychology Suicide - statistics & numerical data Surveys and Questionnaires Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Young Adult |
| title | Psychiatric context of Human Immunodeficiency Virus infection among former plasma donors in rural China |
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