Pharmacological maintenance of protein homeostasis could postpone age‐related disease

Summary Over the last 10 years, various screens of small molecules have been conducted to find long sought interventions in aging. Most of these studies were performed in invertebrates but the demonstration of pharmacological lifespan extension in the mouse has created considerable excitement. Since...

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Veröffentlicht in:	Aging cell 2012-04, Vol.11 (2), p.187-191
Hauptverfasser:	Alavez, Silvestre, Lithgow, Gordon J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals anti‐aging C. elegans disease Disease Models, Animal Homeostasis Humans lifespan longevity regulation mammals Proteins - metabolism
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