Genome-Wide Meta-Analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL

Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease affecting up to 30% of psoriasis vulgaris (PsV) cases and approximately 0.25 to 1% of the general population. To identify common susceptibility loci, we performed a meta-analysis of three imputed genome-wide association stud...

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Veröffentlicht in:	Journal of investigative dermatology 2012-04, Vol.132 (4), p.1133-1140
Hauptverfasser:	Ellinghaus, Eva, Stuart, Philip E., Ellinghaus, David, Nair, Rajan P., Debrus, Sophie, Raelson, John V., Belouchi, Majid, Tejasvi, Trilokraj, Li, Yanming, Tsoi, Lam C., Onken, Anna T., Esko, Tonu, Metspalu, Andres, Rahman, Proton, Gladman, Dafna D., Bowcock, Anne M., Helms, Cynthia, Krueger, Gerald G., Koks, Sulev, Kingo, Külli, Gieger, Christian, Erich Wichmann, H., Mrowietz, Ulrich, Weidinger, Stephan, Schreiber, Stefan, Abecasis, Gonçalo R., Elder, James T., Weichenthal, Michael, Franke, Andre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Arthritis, Psoriatic - genetics Biological and medical sciences Canada Case-Control Studies Dermatology Diseases of the osteoarticular system Diseases of the spine Estonia Genes, rel - genetics Genetic Predisposition to Disease - genetics Genome-Wide Association Study Genotype Germany Humans Inflammatory diseases Inflammatory joint diseases Medical sciences NF- Kappa B protein Polymorphism, Single Nucleotide - genetics psoriasis vulgaris Psoriasis. Parapsoriasis. Lichen Replication Reviews Rheumatoid arthritis Single-nucleotide polymorphism Susceptibility United States Young Adult
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