Inflammatory pseudotumor of the spleen: review of clinical presentation and diagnostic methods
We describe a 91-year-old woman with a clinical history of invasive ductal carcinoma of the breast diagnosed in 1991 who was admitted because of dizziness, poor appetite, and some swelling and tenderness over her cheeks. The patient's initial work up revealed a 5-cm well-demarcated hypodense so...
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description | We describe a 91-year-old woman with a clinical history of invasive ductal carcinoma of the breast diagnosed in 1991 who was admitted because of dizziness, poor appetite, and some swelling and tenderness over her cheeks. The patient's initial work up revealed a 5-cm well-demarcated hypodense solid lesion in her spleen with abnormally intense uptake on PET/CT scan raising suspicion for malignancy i.e. breast metastasis versus lymphoma. Further review demonstrated the presence of this splenic lesion, though slightly smaller, on a CT scan from ten years earlier (2000). An ultrasonographic guided core needle splenic biopsy was performed and the pathology result revealed histological findings compatible with inflammatory pseudotumor of the spleen. As a result, unnecessary splenectomy was avoided. |
doi_str_mv | 10.3941/jrcr.v5i9.758 |
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The patient's initial work up revealed a 5-cm well-demarcated hypodense solid lesion in her spleen with abnormally intense uptake on PET/CT scan raising suspicion for malignancy i.e. breast metastasis versus lymphoma. Further review demonstrated the presence of this splenic lesion, though slightly smaller, on a CT scan from ten years earlier (2000). An ultrasonographic guided core needle splenic biopsy was performed and the pathology result revealed histological findings compatible with inflammatory pseudotumor of the spleen. As a result, unnecessary splenectomy was avoided.</description><identifier>ISSN: 1943-0922</identifier><identifier>EISSN: 1943-0922</identifier><identifier>DOI: 10.3941/jrcr.v5i9.758</identifier><identifier>PMID: 22470813</identifier><language>eng</language><publisher>United States: EduRad</publisher><subject>Aged, 80 and over ; Biopsy, Needle ; Female ; Granuloma, Plasma Cell - diagnostic imaging ; Granuloma, Plasma Cell - pathology ; Humans ; Multimodal Imaging ; Nuclear Medicine ; Positron-Emission Tomography ; Spleen - diagnostic imaging ; Spleen - pathology ; Splenic Diseases - diagnosis ; Tomography, X-Ray Computed</subject><ispartof>Journal of radiology case reports, 2011-09, Vol.5 (9), p.16-22</ispartof><rights>Copyright Journal of Radiology Case Reports 2011</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-1430515b47880d7309d9ee4de0bd29542ad4ba4159f8ffa4b030d9b0e9453f1d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303459/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303459/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22470813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yarmohammadi, Hooman</creatorcontrib><creatorcontrib>Nakamoto, Dean</creatorcontrib><creatorcontrib>Faulhaber, Peter F</creatorcontrib><creatorcontrib>Miedler, John</creatorcontrib><creatorcontrib>Azar, Nami</creatorcontrib><title>Inflammatory pseudotumor of the spleen: review of clinical presentation and diagnostic methods</title><title>Journal of radiology case reports</title><addtitle>J Radiol Case Rep</addtitle><description>We describe a 91-year-old woman with a clinical history of invasive ductal carcinoma of the breast diagnosed in 1991 who was admitted because of dizziness, poor appetite, and some swelling and tenderness over her cheeks. The patient's initial work up revealed a 5-cm well-demarcated hypodense solid lesion in her spleen with abnormally intense uptake on PET/CT scan raising suspicion for malignancy i.e. breast metastasis versus lymphoma. Further review demonstrated the presence of this splenic lesion, though slightly smaller, on a CT scan from ten years earlier (2000). An ultrasonographic guided core needle splenic biopsy was performed and the pathology result revealed histological findings compatible with inflammatory pseudotumor of the spleen. As a result, unnecessary splenectomy was avoided.</description><subject>Aged, 80 and over</subject><subject>Biopsy, Needle</subject><subject>Female</subject><subject>Granuloma, Plasma Cell - diagnostic imaging</subject><subject>Granuloma, Plasma Cell - pathology</subject><subject>Humans</subject><subject>Multimodal Imaging</subject><subject>Nuclear Medicine</subject><subject>Positron-Emission Tomography</subject><subject>Spleen - diagnostic imaging</subject><subject>Spleen - pathology</subject><subject>Splenic Diseases - diagnosis</subject><subject>Tomography, X-Ray Computed</subject><issn>1943-0922</issn><issn>1943-0922</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU1LxDAQhoMoun4cvUpunromTdI2HgQRv0DwoldD2kx3I21Sk3TFf28XdVlPM8w8vDPwIHRKyZxJTi_eQxPmK2HlvBTVDppRyVlGZJ7vbvUH6DDGd0KKohBsHx3kOS9JRdkMvT26ttN9r5MPX3iIMBqfxt4H7FucloDj0AG4SxxgZeFzPW0662yjOzwEiOCSTtY7rJ3BxuqF8zHZBveQlt7EY7TX6i7CyW89Qq93ty83D9nT8_3jzfVT1nCRp4xyRgQVNS-ripiSEWkkADdAapNLwXNteK05FbKt2lbzmjBiZE1AcsFaatgRuvrJHca6B9NMbwXdqSHYXocv5bVV_zfOLtXCrxRjhHEhp4Dz34DgP0aISfU2NtB12oEfo5IFz4koSDmR2Q_ZBB9jgHZzhRK1VqLWStRaiZqUTPzZ9msb-s8B-wavg4vB</recordid><startdate>20110901</startdate><enddate>20110901</enddate><creator>Yarmohammadi, Hooman</creator><creator>Nakamoto, Dean</creator><creator>Faulhaber, Peter F</creator><creator>Miedler, John</creator><creator>Azar, Nami</creator><general>EduRad</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110901</creationdate><title>Inflammatory pseudotumor of the spleen: review of clinical presentation and diagnostic methods</title><author>Yarmohammadi, Hooman ; Nakamoto, Dean ; Faulhaber, Peter F ; Miedler, John ; Azar, Nami</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-1430515b47880d7309d9ee4de0bd29542ad4ba4159f8ffa4b030d9b0e9453f1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aged, 80 and over</topic><topic>Biopsy, Needle</topic><topic>Female</topic><topic>Granuloma, Plasma Cell - diagnostic imaging</topic><topic>Granuloma, Plasma Cell - pathology</topic><topic>Humans</topic><topic>Multimodal Imaging</topic><topic>Nuclear Medicine</topic><topic>Positron-Emission Tomography</topic><topic>Spleen - diagnostic imaging</topic><topic>Spleen - pathology</topic><topic>Splenic Diseases - diagnosis</topic><topic>Tomography, X-Ray Computed</topic><toplevel>online_resources</toplevel><creatorcontrib>Yarmohammadi, Hooman</creatorcontrib><creatorcontrib>Nakamoto, Dean</creatorcontrib><creatorcontrib>Faulhaber, Peter F</creatorcontrib><creatorcontrib>Miedler, John</creatorcontrib><creatorcontrib>Azar, Nami</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of radiology case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yarmohammadi, Hooman</au><au>Nakamoto, Dean</au><au>Faulhaber, Peter F</au><au>Miedler, John</au><au>Azar, Nami</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inflammatory pseudotumor of the spleen: review of clinical presentation and diagnostic methods</atitle><jtitle>Journal of radiology case reports</jtitle><addtitle>J Radiol Case Rep</addtitle><date>2011-09-01</date><risdate>2011</risdate><volume>5</volume><issue>9</issue><spage>16</spage><epage>22</epage><pages>16-22</pages><issn>1943-0922</issn><eissn>1943-0922</eissn><abstract>We describe a 91-year-old woman with a clinical history of invasive ductal carcinoma of the breast diagnosed in 1991 who was admitted because of dizziness, poor appetite, and some swelling and tenderness over her cheeks. The patient's initial work up revealed a 5-cm well-demarcated hypodense solid lesion in her spleen with abnormally intense uptake on PET/CT scan raising suspicion for malignancy i.e. breast metastasis versus lymphoma. Further review demonstrated the presence of this splenic lesion, though slightly smaller, on a CT scan from ten years earlier (2000). An ultrasonographic guided core needle splenic biopsy was performed and the pathology result revealed histological findings compatible with inflammatory pseudotumor of the spleen. As a result, unnecessary splenectomy was avoided.</abstract><cop>United States</cop><pub>EduRad</pub><pmid>22470813</pmid><doi>10.3941/jrcr.v5i9.758</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged, 80 and over Biopsy, Needle Female Granuloma, Plasma Cell - diagnostic imaging Granuloma, Plasma Cell - pathology Humans Multimodal Imaging Nuclear Medicine Positron-Emission Tomography Spleen - diagnostic imaging Spleen - pathology Splenic Diseases - diagnosis Tomography, X-Ray Computed |
title | Inflammatory pseudotumor of the spleen: review of clinical presentation and diagnostic methods |
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