Laforin, a dual specificity protein phosphatase involved in Lafora disease, is phosphorylated at Ser25 by AMP-activated protein kinase

Lafora progressive myoclonus epilepsy (Lafora disease; LD) is a fatal autosomal recessive neurodegenerative disorder caused by loss-of-function mutations in either the EPM2A gene, encoding the dual specificity phosphatase laforin, or the EPM2B gene, encoding the E3-ubiquitin ligase malin. Previously...

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Veröffentlicht in:	Biochemical journal 2011-10, Vol.439 (2), p.265-275
Hauptverfasser:	Romá-Mateo, Carlos, Solaz-Fuster, Mari Carmen, Gimeno-Alcañiz, José V, Dukhande, Vikas, Donderis, Jordi, Marina, Alberto, Criado, Olga, Koller, Antonius, Rodriguez de Cordoba, Santiago, Gentry, Matthew S, Sanz, Pascual
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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