Role of Cardiac Stem Cells in Cardiac Pathophysiology: A Paradigm Shift in Human Myocardial Biology

For nearly a century, the human heart has been viewed as a terminally differentiated postmitotic organ in which the number of cardiomyocytes is established at birth, and these cells persist throughout the lifespan of the organ and organism. However, the discovery that cardiac stem cells live in the...

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Veröffentlicht in:	Circulation research 2011-09, Vol.109 (8), p.941-961
Hauptverfasser:	Leri, Annarosa, Kajstura, Jan, Anversa, Piero
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptations Adult Stem Cells - cytology Adult Stem Cells - physiology Aging Animals Biological and medical sciences Birth cardiomyocytes Cell Differentiation - physiology Cell Enlargement Cell lineage Fundamental and applied biological sciences. Psychology Heart Heart diseases Heart Diseases - physiopathology Humans Hypertrophy Injuries Life span Myocardium - cytology Myocytes Myocytes, Cardiac - cytology Myocytes, Cardiac - physiology Stem cells Stem Cells - cytology Stem Cells - physiology Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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