Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT

Fibroblasts are responsible for producing the majority of collagen and other extracellular matrix (ECM) proteins in tissues. In the injured tissue, transforming growth factor-β (TGF-β)-activated fibroblasts or differentiated myofibroblasts synthesize excessive ECM proteins and play a pivotal role in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cellular signalling 2012-05, Vol.24 (5), p.1031-1036
Hauptverfasser:	Ghosh, Asish K., Nagpal, Varun, Covington, Joseph W., Michaels, Marissa A., Vaughan, Douglas E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATp300 Benzamides - pharmacology Cardiac EndMT Cell Transdifferentiation Cells, Cultured Dioxoles - pharmacology Endothelial Cells - drug effects Endothelial Cells - metabolism Endothelial Cells - physiology Epigenetics Extracellular Signal-Regulated MAP Kinases - metabolism Fibrosis Flavonoids - pharmacology Gene Expression Regulation MAP Kinase Kinase Kinases - antagonists & inhibitors MAP Kinase Kinase Kinases - metabolism Mice MicroRNA MicroRNAs - genetics Myocardium - pathology p300-CBP Transcription Factors - metabolism Receptors, Transforming Growth Factor beta - antagonists & inhibitors Receptors, Transforming Growth Factor beta - metabolism TβRI kinase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!