A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13

The genetic risk factors for chronic obstructive pulmonary disease (COPD) are still largely unknown. To date, genome-wide association studies (GWASs) of limited size have identified several novel risk loci for COPD at CHRNA3/CHRNA5/IREB2, HHIP and FAM13A; additional loci may be identified through la...

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Veröffentlicht in:	Human molecular genetics 2012-02, Vol.21 (4), p.947-957
Hauptverfasser:	Cho, Michael H., Castaldi, Peter J., Wan, Emily S., Siedlinski, Mateusz, Hersh, Craig P., Demeo, Dawn L., Himes, Blanca E., Sylvia, Jody S., Klanderman, Barbara J., Ziniti, John P., Lange, Christoph, Litonjua, Augusto A., Sparrow, David, Regan, Elizabeth A., Make, Barry J., Hokanson, John E., Murray, Tanda, Hetmanski, Jacqueline B., Pillai, Sreekumar G., Kong, Xiangyang, Anderson, Wayne H., Tal-Singer, Ruth, Lomas, David A., Coxson, Harvey O., Edwards, Lisa D., MacNee, William, Vestbo, Jørgen, Yates, Julie C., Agusti, Alvar, Calverley, Peter M.A., Celli, Bartolome, Crim, Courtney, Rennard, Stephen, Wouters, Emiel, Bakke, Per, Gulsvik, Amund, Crapo, James D., Beaty, Terri H., Silverman, Edwin K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Association Studies Chromosomes, Human, Pair 19 - genetics Follow-Up Studies Genetic Predisposition to Disease - genetics Genome-Wide Association Study Genotyping Techniques Humans Pulmonary Disease, Chronic Obstructive - genetics
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