3D Imaging by Mass Spectrometry: A New Frontier
Imaging mass spectrometry can generate three-dimensional volumes showing molecular distributions in an entire organ or animal through registration and stacking of serial tissue sections. Here, we review the current state of 3D imaging mass spectrometry as well as provide insights and perspectives on...
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| Veröffentlicht in: | Analytical chemistry (Washington) 2012-03, Vol.84 (5), p.2105-2110 |
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| container_title | Analytical chemistry (Washington) |
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| creator | SEELEY, Erin H CAPRIOLI, Richard M |
| description | Imaging mass spectrometry can generate three-dimensional volumes showing molecular distributions in an entire organ or animal through registration and stacking of serial tissue sections. Here, we review the current state of 3D imaging mass spectrometry as well as provide insights and perspectives on the process of generating 3D mass spectral data along with a discussion of the process necessary to generate a 3D image volume. |
| doi_str_mv | 10.1021/ac2032707 |
| format | Article |
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| ispartof | Analytical chemistry (Washington), 2012-03, Vol.84 (5), p.2105-2110 |
| issn | 0003-2700 1520-6882 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3296907 |
| source | MEDLINE; American Chemical Society Publications |
| subjects | Analytical chemistry Animals Brain - anatomy & histology Chemistry Exact sciences and technology Humans Imaging, Three-Dimensional Magnetic Resonance Imaging Peptides - chemistry Proteins - chemistry Spectrometric and optical methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spectrometry, Mass, Secondary Ion |
| title | 3D Imaging by Mass Spectrometry: A New Frontier |
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