Incidence of EGFR Exon 19 Deletions and L858R in Tumor Specimens From Men and Cigarette Smokers With Lung Adenocarcinomas

EGFR mutations underlie the sensitivity of lung cancers to erlotinib and gefitinib and can occur in any patient with this illness. Here we examine the frequency of EGFR mutations in smokers and men. We determined the frequency of EGFR mutations and characterized their association with cigarette smok...

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Veröffentlicht in:Journal of clinical oncology 2011-05, Vol.29 (15), p.2066-2070
Hauptverfasser: D'ANGELO, Sandra P, CATHERINE PIETANZA, M, JOHNSON, Melissa L, RIELY, Gregory J, MILLER, Vincent A, SIMA, Camelia S, ZAKOWSKI, Maureen F, RUSCH, Valerie W, LADANYI, Marc, KRIS, Mark G
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Sprache:eng
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