Biliary physiology in rats with bile ductular cell hyperplasia: evidence for a secretory function of proliferated bile ductules

To establish the role of the biliary epithelium in bile formation, we studied several aspects of biliary physiology in control rats and in rats with ductular cell hyperplasia induced by a 14-d extrahepatic biliary obstruction. Under steady-state conditions, spontaneous bile flow was far greater in o...

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Veröffentlicht in:	The Journal of clinical investigation 1988-02, Vol.81 (2), p.569-578
Hauptverfasser:	ALPINI, G, LENZI, R, SARKOZI, L, TAVOLONI, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Amylases - metabolism Animals Bile - metabolism Bile Ducts - pathology Bile Ducts - physiopathology Biological and medical sciences Cholestasis, Extrahepatic - pathology Cholestasis, Extrahepatic - physiopathology gamma-Glutamyltransferase - metabolism Gastroenterology. Liver. Pancreas. Abdomen Hyperplasia Liver - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Mannitol - pharmacokinetics Medical sciences Other diseases. Semiology Rats Secretin - pharmacology Sucrose - pharmacokinetics Taurocholic Acid - pharmacology
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