p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis

► Timely separation of the developing pituitary from the oral ectoderm relies on p21. ► p27 and p21 do not act synergistically to restrain pituitary proliferation. ► p21 is necessary to maintain basal levels of cell cycle machinery components. A delicate balance between proliferation and differentia...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mechanisms of development 2012-01, Vol.128 (11-12), p.640-652
Hauptverfasser: Monahan, Pamela, Himes, Ashley D., Parfieniuk, Agata, Raetzman, Lori T.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!