Theoretical analysis of library screening using a N-dimensional pooling strategy

A solution to the problem of library screening is analysed. We examine how to retrieve those clones that are positive for a single copy landmark from a whole library while performing only a minimum number of laboratory tests: the clones are arranged on a matrix (i.e in 2 dimensions) and pooled accor...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 1991-11, Vol.19 (22), p.6241-6247
Hauptverfasser:	BARILLOT, E, LACROIX, B, COHEN, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biotechnology Chromosome Mapping Chromosomes, Fungal Fundamental and applied biological sciences. Psychology Genetic engineering Genetic technics Genome, Human Genomic Library Humans Methods. Procedures. Technologies Restriction Mapping Synthetic digonucleotides and genes. Sequencing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!