Signaling Mechanisms in the Regulation of Renal Matrix Metabolism in Diabetes

Renal hypertrophy and accumulation of extracellular matrix proteins are among cardinal manifestations of diabetic nephropathy. TGF beta system has been implicated in the pathogenesis of these manifestations. Among signaling pathways activated in the kidney in diabetes, mTOR- (mammalian target of rap...

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Veröffentlicht in:	Experimental diabetes research 2012-01, Vol.2012 (2012), p.1-10
1. Verfasser:	Mariappan, Meenalakshmi M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Diabetic Nephropathies - metabolism Extracellular Matrix - metabolism Humans Kidney - metabolism Review Signal Transduction - physiology
Online-Zugang:	Volltext
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