Regional function-structure relationships in lungs of an elastase murine model of emphysema

Changes in lung function and structure were studied using hyperpolarized (3)He MRI in an elastase-induced murine model of emphysema. The combined analysis of the apparent diffusion coefficient (ADC) and fractional ventilation (R) were used to distinguish emphysematous changes and also to develop a m...

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Veröffentlicht in:Journal of applied physiology (1985) 2012-01, Vol.112 (1), p.135-148
Hauptverfasser: ISHII, Masaru, EMAMI, Kiarash, KUZMA, Nicholas, KADLECEK, Stephen, PODOLIN, Patricia L, RIZI, Rahim R, YI XIN, BARULIC, Amy, KOTZER, Charles J, LOGAN, Gregory A, CHIA, Elaine, MACDUFFIE-WOODBURN, John P, JIANLIANG ZHU, PICKUP, Stephen
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Sprache:eng
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