Effects of exposure to amphetamine derivatives on passive avoidance performance and the central levels of monoamines and their metabolites in mice: Correlations between behavior and neurochemistry

Rationale Considerable evidence indicates that amphetamine derivatives can deplete brain monoaminergic neurotransmitters. However, the behavioral and cognitive consequences of neurochemical depletions induced by amphetamines are not well established. Objectives In this study, mice were exposed to do...

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Veröffentlicht in:	Psychopharmacologia 2012-04, Vol.220 (3), p.495-508
Hauptverfasser:	Murnane, Kevin Sean, Perrine, Shane Alan, Finton, Brendan James, Galloway, Matthew Peter, Howell, Leonard Lee, Fantegrossi, William Edward
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adrenergic Agents - administration & dosage Adrenergic Agents - toxicity Adult and adolescent clinical studies Amphetamine Amphetamines Amygdala Analysis Animal behavior Animals Avoidance behavior Avoidance Learning - drug effects Behavior Behavior, Animal - drug effects Biological and medical sciences Biomedical and Life Sciences Biomedicine Brain Brain - drug effects Brain - metabolism Chromatography, High Pressure Liquid Cognitive ability Cortex (cingulate) Cortex (frontal) Dopamine Dopamine - metabolism Dose-Response Relationship, Drug Drug abuse Drug addiction Ecstasy (Drug) High-performance liquid chromatography Hippocampus Learning Linear Models Male MDMA Medical sciences Memory Memory - drug effects Metabolites Methamphetamine Methamphetamine - administration & dosage Methamphetamine - toxicity Mice monoamines N-Methyl-3,4-methylenedioxyamphetamine - administration & dosage N-Methyl-3,4-methylenedioxyamphetamine - toxicity Neostriatum Neurochemistry Neuropharmacology Neurosciences Neurotoxicity Neurotransmitters Original Investigation p-Chloroamphetamine - administration & dosage p-Chloroamphetamine - toxicity parachloroamphetamine Pharmacology. Drug treatments Pharmacology/Toxicology Plant metabolites Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Regression analysis Resveratrol Serotonin Serotonin - metabolism Serotonin Agents - administration & dosage Serotonin Agents - toxicity
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