Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds

Injectable scaffolds present compelling opportunities for wound repair and regeneration because of their ability to fill irregularly shaped defects and deliver biologics such as growth factors. In this study, we investigated the properties of injectable polyurethane (PUR) biocomposite scaffolds and...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2012-02, Vol.100A (2), p.450-461
Hauptverfasser:	Adolph, Elizabeth J., Hafeman, Andrea E., Davidson, Jeffrey M., Nanney, Lillian B., Guelcher, Scott A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Biological and medical sciences Biotechnology Carboxymethylcellulose Sodium - chemistry Cell Proliferation - drug effects Collagen - biosynthesis Disease Models, Animal Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Hyaluronic Acid - chemistry Immunohistochemistry Industrial applications and implications. Economical aspects injectable scaffolds Injections Isocyanates - chemistry Ki-67 Antigen - metabolism Lysine - analogs & derivatives Lysine - chemistry Male Medical sciences Miscellaneous Polyethylene Glycols - chemistry polyurethane Polyurethanes - pharmacology Rats, Sprague-Dawley regeneration Rheology - drug effects Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments tissue engineering Tissue Scaffolds - chemistry wound healing Wound Healing - drug effects Wounds and Injuries - pathology
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