EGFL7: a unique angiogenic signaling factor in vascular development and disease

EGFL7 is a secreted angiogenic factor that is highly conserved in vertebrates. Most secreted angiogenic signaling molecules, including VEGF and fibroblast growth factor-2, are mainly expressed by nonendothelial cell types such as fibroblasts. In contrast, EGFL7 is unique because it is almost exclusi...

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Veröffentlicht in:	Blood 2012-02, Vol.119 (6), p.1345-1352
Hauptverfasser:	Nichol, Donna, Stuhlmann, Heidi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inducing Agents - metabolism Animals Biological and medical sciences Blood Vessels - growth & development Blood Vessels - metabolism Calcium-Binding Proteins Cell Movement Cell Proliferation EGF Family of Proteins Endothelial Growth Factors - metabolism Endothelium, Vascular - cytology Endothelium, Vascular - growth & development Endothelium, Vascular - metabolism Hematologic and hematopoietic diseases Humans Medical sciences Models, Biological Review Signal Transduction
Online-Zugang:	Volltext
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