Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

Enterovirus infections have been linked to type 1 diabetes in several studies. Enteroviruses also have tropism to pancreatic islets and can cause β-cell damage in experimental models. Viral persistence has been suspected to be an important pathogenetic factor. This study evaluates whether gut mucosa...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2012-03, Vol.61 (3), p.687-691
Hauptverfasser:	OIKARINEN, Maarit, TAURIAINEN, Sisko, OIKARINEN, Sami, HONKANEN, Teemu, COLLIN, Pekka, RANTALA, Immo, MÄKI, Markku, KAUKINEN, Katri, HYÖTY, Heikki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies Biological and medical sciences Biopsy Celiac disease Diabetes Diabetes Mellitus, Type 1 - etiology Diabetes Mellitus, Type 1 - virology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enterovirus Enterovirus - isolation & purification Enterovirus diseases Enterovirus infections Enterovirus Infections - complications Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Health aspects HLA-DR Antigens - analysis Humans Hybridization Immune system In Situ Hybridization Infections Inflammation Inflammatory bowel disease Intestinal Mucosa - virology Male Medical sciences Pancreas Pathophysiology Polymerase Chain Reaction Risk factors RNA, Viral - analysis Type 1 diabetes
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