Early Age at Time of Primary Epstein-Barr Virus Infection Results in Poorly Controlled Viral Infection in Infants From Western Kenya: Clues to the Etiology of Endemic Burkitt Lymphoma

Background. Infection with Epstein-Barr virus (EBV) early in life and repeated malaria exposure have been proposed as risk factors for endemic Burkitt lymphoma (eBL). Methods. Infants were enrolled from 2 rural sites in Kenya: the Kisumu District, where malaria transmission is holoendemic and risk f...

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Veröffentlicht in:	The Journal of infectious diseases 2012-03, Vol.205 (6), p.906-913
Hauptverfasser:	Piriou, Erwan, Asito, Amolo S., Sumba, Peter O., Fiore, Nancy, Middeldorp, Jaap M., Moormann, Ann M., Ploutz-Snyder, Robert, Rochford, Rosemary
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Viral - blood Biological and medical sciences Burkitt lymphoma Burkitt Lymphoma - epidemiology Burkitt Lymphoma - etiology Burkitt Lymphoma - virology Child, Preschool Children Disease transmission DNA, Protozoan - blood DNA, Viral - blood Epstein Barr virus infections Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - epidemiology Female Fundamental and applied biological sciences. Psychology Geography Herpesvirus 4, Human - immunology Herpesvirus 4, Human - pathogenicity Human herpesvirus 4 Humans Infant Infants Infections Infectious diseases Kenya - epidemiology Longitudinal Studies Major and Brief Reports Malaria Malaria - complications Malaria - epidemiology Malaria - virology Male Medical sciences Microbiology Miscellaneous Parasitemia - complications Parasitemia - epidemiology Parasitemia - virology Viral Load Virology VIRUSES
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