IL-10 Contributes to the Suppressive Function of Tumour-Associated Myeloid Cells and Enhances Myeloid Cell Accumulation in Tumours

Studies have revealed that tumour‐associated myeloid cells (TAMC) are one of the major sources of IL‐10 in tumour‐bearing mice. However, the significance of TAMC‐derived IL‐10 in tumour immunity is poorly understood. Here, we show that IL‐10 blockade or IL‐10 deficiency reduces the capacity of TAMC...

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