Antiplatelet drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

The article describes the mechanisms of action, pharmacokinetics, and pharmacodynamics of aspirin, dipyridamole, cilostazol, the thienopyridines, and the glycoprotein IIb/IIIa antagonists. The relationships among dose, efficacy, and safety are discussed along with a mechanistic overview of results o...

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Veröffentlicht in:	Chest 2012-02, Vol.141 (2 Suppl), p.e89S-e119S
Hauptverfasser:	Eikelboom, John W, Hirsh, Jack, Spencer, Frederick A, Baglin, Trevor P, Weitz, Jeffrey I
Format:	Artikel
Sprache:	eng
Schlagworte:	Antithrombotic Therapy and Prevention of Thrombosis, 9th Ed: American College of Chest Physician Evidence-Based Clinical Practice Guidelines Online Only Aspirin - adverse effects Aspirin - pharmacokinetics Aspirin - therapeutic use Dipyridamole - adverse effects Dipyridamole - pharmacokinetics Dipyridamole - therapeutic use Dose-Response Relationship, Drug Drug Therapy, Combination Evidence-Based Medicine Humans Platelet Activation - drug effects Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - adverse effects Platelet Aggregation Inhibitors - pharmacokinetics Platelet Aggregation Inhibitors - therapeutic use Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors Practice Guidelines as Topic Randomized Controlled Trials as Topic Societies, Medical Tetrazoles - adverse effects Tetrazoles - pharmacokinetics Tetrazoles - therapeutic use Thienopyridines - adverse effects Thienopyridines - pharmacokinetics Thienopyridines - therapeutic use Thrombosis - blood Thrombosis - drug therapy Thrombosis - prevention & control United States
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