The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma

In follow-up of a recent genome-wide association study (GWAS) that identified a locus in chromosome 2p21 associated with risk for renal cell carcinoma (RCC), we conducted a fine mapping analysis of a 120 kb region that includes EPAS1. We genotyped 59 tagged common single-nucleotide polymorphisms (SN...

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Veröffentlicht in:	Human molecular genetics 2012-03, Vol.21 (5), p.1190-1200
Hauptverfasser:	Han, Summer S., Yeager, Meredith, Moore, Lee E., Wei, Ming-Hui, Pfeiffer, Ruth, Toure, Ousmane, Purdue, Mark P., Johansson, Mattias, Scelo, Ghislaine, Chung, Charles C., Gaborieau, Valerie, Zaridze, David, Schwartz, Kendra, Szeszenia-Dabrowska, Neonilia, Davis, Faith, Bencko, Vladimir, Colt, Joanne S., Janout, Vladimir, Matveev, Vsevolod, Foretova, Lenka, Mates, Dana, Navratilova, M., Boffetta, Paolo, Berg, Christine D., Grubb, Robert L., Stevens, Victoria L., Thun, Michael J., Diver, W. Ryan, Gapstur, Susan M., Albanes, Demetrius, Weinstein, Stephanie J., Virtamo, Jarmo, Burdett, Laurie, Brisuda, Antonin, McKay, James D., Fraumeni, Joseph F., Chatterjee, Nilanjan, Rosenberg, Philip S., Rothman, Nathaniel, Brennan, Paul, Chow, Wong-Ho, Tucker, Margaret A., Chanock, Stephen J., Toro, Jorge R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Association Studies Basic Helix-Loop-Helix Transcription Factors - genetics Carcinoma, Renal Cell - genetics Case-Control Studies Chromosome Mapping Chromosomes, Human, Pair 2 - genetics Female Genetic Predisposition to Disease Genotype Haplotypes HapMap Project Humans Kidney Neoplasms - genetics Male Polymorphism, Single Nucleotide Smoking
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