Functionally impaired tRNA from ethionine treated rats as detected in injected Xenopus oocytes

Treatment of rats with ethionine was found to cause severe impairment in the aminoacylation capacity of tRNA. This effect was only observed when assayed in injected oocytes, while in vitro assays of aminoacylation failed to detect differences between normal tRNA and tRNA from ethionine treated anima...

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Veröffentlicht in:	Nucleic acids research 1979-02, Vol.6 (2), p.657-672
Hauptverfasser:	Ginzburg, Irith, Cornelis, Pierre, Giveon, David, Littauer, Uriel Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acyl-tRNA Synthetases - metabolism Animals Ethionine - pharmacology Female Kinetics Liver - drug effects Liver - metabolism Oocytes - metabolism Ovum - metabolism Protein Biosynthesis - drug effects Rats RNA, Transfer - metabolism RNA, Transfer, Amino Acyl - biosynthesis Triticum aestivum Xenopus
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