SREBPs: metabolic integrators in physiology and metabolism

Recent advances have significantly increased our understanding of how sterol regulatory element binding proteins (SREBPs) are regulated at the transcriptional and post-transcriptional levels in response to cellular signaling. The phosphatidyl inositol-3-kinase (PI3K) and SREBP pathways intersect at...

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Veröffentlicht in:	Trends in endocrinology and metabolism 2012-02, Vol.23 (2), p.65-72
Hauptverfasser:	Jeon, Tae-Il, Osborne, Timothy F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy - physiology Biological and medical sciences Cell Nucleus - metabolism Endocrinology & Metabolism Fundamental and applied biological sciences. Psychology Humans Immunity, Innate - physiology Lipid Metabolism - drug effects Lipid Metabolism - physiology Liver - drug effects Liver - metabolism MicroRNAs - physiology Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism Signal Transduction - physiology Sterol Regulatory Element Binding Protein 1 - physiology Sterol Regulatory Element Binding Protein 2 - physiology Sterol Regulatory Element Binding Proteins - physiology Sulfotransferases - metabolism Unfolded Protein Response - physiology Vertebrates: endocrinology
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