Satellite DNA relationships in man and the primates

We have investigated the genomes of a series of primates to identify the presence of sequences related to human satellite DNAs I, II and III by restriction enzyme digestion and hybridisation with probes of these satellite DNAs. Where we have found such related sequences we have examined the extent t...

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Veröffentlicht in:Nucleic acids research 1981-07, Vol.9 (14), p.3235-3249
Hauptverfasser: Mitchell, A.R., Gosden, J.R., Ryder, O.A.
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creator Mitchell, A.R.
Gosden, J.R.
Ryder, O.A.
description We have investigated the genomes of a series of primates to identify the presence of sequences related to human satellite DNAs I, II and III by restriction enzyme digestion and hybridisation with probes of these satellite DNAs. Where we have found such related sequences we have examined the extent to which they have diverged by measuring the stability of the hybrids. DNA satellite III is the oldest sequence being common to species which have diverged some 24 million years ago. In contrast DNA satellites I and II are of much more recent origin. Our results permit us to draw conclusions about the way these sequences have evolved, and how the evolution of repeated DNA sequences may be related to the evolution of the primate lineage.
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source Oxford University Press Journals Digital Archive legacy; MEDLINE; PubMed Central
subjects Animals
DNA Restriction Enzymes
DNA, Satellite - genetics
Gorilla gorilla - genetics
Humans
Hylobates - genetics
Male
Nucleic Acid Hybridization
Pan troglodytes - genetics
Pongo pygmaeus - genetics
Primates
Primates - genetics
Species Specificity
Spleen
title Satellite DNA relationships in man and the primates
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