Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

Salmonella infection is a common complication in people with malaria. Here the authors show that induction of heme oxygenase-1, a mechanism of tolerance to malaria, impairs resistance to Salmonella infection by limiting production of bactericidal reactive oxygen species. In sub-Saharan Africa, invas...

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Veröffentlicht in:Nature medicine 2012-01, Vol.18 (1), p.120-127
Hauptverfasser: Cunnington, Aubrey J, de Souza, J Brian, Walther, Michael, Riley, Eleanor M
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Sprache:eng
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