Bim and Bmf in tissue homeostasis and malignant disease

Among all BH3-only proteins known to date, most information is available on the biological role and function of Bim (Bcl-2 interacting mediator of cell death)/BOD (Bcl-2 related ovarian death agonist), whereas little is still known about its closest relative, Bcl-2 modifying factor (Bmf). Although B...

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Veröffentlicht in:	Oncogene 2008-12, Vol.27 (S1), p.S41-S52
Hauptverfasser:	Piñon, J D, Labi, V, Egle, A, Villunger, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - chemistry Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - physiology Animals Apoptosis Apoptosis - drug effects Apoptosis - physiology Apoptosis Regulatory Proteins - chemistry Apoptosis Regulatory Proteins - genetics Apoptosis Regulatory Proteins - physiology Autoimmune Diseases - metabolism Bcl-2 protein Bcl-2-Like Protein 11 BIM protein Cancer Cell Biology Cell death Cellular biology Cytokines Gene Expression Regulation Gene Targeting Glucocorticoids Homeostasis Homeostasis - physiology Human Genetics Humans Internal Medicine Lymphocytes - cytology Lymphocytes B Medicine Medicine & Public Health Membrane Proteins - chemistry Membrane Proteins - genetics Membrane Proteins - physiology Mice Mice, Knockout Mitochondria - metabolism Molecular biology Neoplasm Proteins - physiology Neoplasms - metabolism Neoplasms - pathology Neoplasms - therapy Nutrient deficiency Oncology Proteasome Endopeptidase Complex - metabolism Protein Isoforms - physiology Protein Structure, Tertiary Proteins Proto-Oncogene Proteins - chemistry Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - physiology Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors review Signal transduction Tumor Suppressor Proteins - chemistry Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - physiology
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