Sex differences in the behavioral response to methylphenidate in three adolescent rat strains (WKY, SHR, SD)

► Sex plays major role in animal's response to methylphenidate. ► Genotype plays major role in animal's response to methylphenidate. ► Each sex exhibits different dose–response characteristics. ► Each genotype exhibits different dose–response characteristics. ► The highest dose of MPD elic...

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Veröffentlicht in:	Behavioural brain research 2012-01, Vol.226 (1), p.8-17
Hauptverfasser:	Chelaru, Mircea I., Yang, Pamela B., Dafny, Nachum
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescence Animals Attention deficit hyperactivity disorder Behavior, Animal - drug effects Behavioral psychophysiology Biological and medical sciences Central Nervous System Stimulants - pharmacology Children Drugs Female Fundamental and applied biological sciences. Psychology Hormones Locomotor activity Male Medical sciences Methylphenidate Methylphenidate - pharmacology Motor Activity - drug effects Neuropharmacology Open-field activity Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopharmacology Rats Rats, Inbred SHR Rats, Inbred WKY Rats, Sprague-Dawley Ritalin Sex Sex Characteristics Sex differences SHR Species Specificity WKY and SD rats
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