A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo

Sorting nexins （SNXs） are phosphoinositide-binding proteins implicated in the sorting of various membrane pro- teins in vitro, but the in vivo functions of them remain largely unknown. We reported previously that SNX10 is a unique member of the SNX family genes in that it has vacuolation activity in...

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Veröffentlicht in:	Cell research 2012-02, Vol.22 (2), p.333-345
Hauptverfasser:	Chen, Yanqun, Wu, Bin, Xu, Liangliang, Li, Huapeng, Xia, Jianhong, Yin, Wenguang, Li, Zhuo, Shi, Dawei, Li, Song, Lin, Shuo, Shu, Xiaodong, Pei, Duanqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Body Patterning Cell Biology Cell Line, Tumor Centrosome - physiology Cilia - physiology Embryonic Development Embryonic growth stage Humans Life Sciences Membranes Morphogenesis Organs Original original-article Protein Binding Proteins rab GTP-Binding Proteins - metabolism RNA Interference RNA, Small Interfering - metabolism Sorting Nexins - antagonists & inhibitors Sorting Nexins - genetics Sorting Nexins - metabolism V-ATPase V-ATP酶 Vacuolar Proton-Translocating ATPases - antagonists & inhibitors Vacuolar Proton-Translocating ATPases - genetics Vacuolar Proton-Translocating ATPases - metabolism Vacuoles - metabolism Vacuoles - physiology Zebrafish Zebrafish Proteins - antagonists & inhibitors Zebrafish Proteins - genetics Zebrafish Proteins - metabolism 体内体外内脏器官培养细胞胚胎发育过程通路
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