Giant DNA Virus Mimivirus Encodes Pathway for Biosynthesis of Unusual Sugar 4-Amino-4,6-dideoxy-d-glucose (Viosamine)

Mimivirus is one the largest DNA virus identified so far, infecting several Acanthamoeba species. Analysis of its genome revealed the presence of a nine-gene cluster containing genes potentially involved in glycan formation. All of these genes are co-expressed at late stages of infection, suggesting...

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Veröffentlicht in:	The Journal of biological chemistry 2012-01, Vol.287 (5), p.3009-3018
Hauptverfasser:	Piacente, Francesco, Marin, Margherita, Molinaro, Antonio, De Castro, Cristina, Seltzer, Virginie, Salis, Annalisa, Damonte, Gianluca, Bernardi, Cinzia, Claverie, Jean-Michel, Abergel, Chantal, Tonetti, Michela
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Amino-4,6-dideoxyglucose Acanthamoeba - virology Aminotransferase Carbohydrate Biosynthesis DNA Viruses DNA, Viral - genetics DNA, Viral - metabolism Evolution, Molecular GC-MS Genes, Viral - physiology Glucosamine - analogs & derivatives Glucosamine - genetics Glucosamine - metabolism Glycobiology and Extracellular Matrices Glycosylation Mimiviridae - enzymology Mimiviridae - genetics Mimivirus NCLDV NMR Transaminases - genetics Transaminases - metabolism Uridine Diphosphate Sugars - genetics Uridine Diphosphate Sugars - metabolism Viosamine
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