Intensive Diabetes Therapy and Glomerular Filtration Rate in Type 1 Diabetes

Persons with type 1 diabetes are at high risk for kidney disease. In this study, intensive diabetes therapy administered early in the course of type 1 diabetes reduced the long-term risk of an impaired glomerular filtration rate. An impaired glomerular filtration rate (GFR) is the final common pathw...

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Veröffentlicht in:	The New England journal of medicine 2011-12, Vol.365 (25), p.2366-2376
Hauptverfasser:	de Boer, Ian H, Sun, Wanjie, Cleary, Patricia A, Lachin, John M, Molitch, Mark E, Steffes, Michael W, Zinman, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiovascular disease Cardiovascular diseases Creatinine Creatinine - blood Data processing Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 1 - physiopathology Diabetes. Impaired glucose tolerance Diabetic Nephropathies - epidemiology Disease prevention End-stage renal disease Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance Excretion Female Follow-Up Studies General aspects Glomerular filtration rate Glomerular Filtration Rate - drug effects Glycated Hemoglobin A - analysis Hemoglobin Humans Hypoglycemic Agents - administration & dosage Insulin - administration & dosage Insulin Infusion Systems Kidney diseases Kidney Failure, Chronic - epidemiology Long-term effects Male Medical sciences Middle Aged
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