Impact of Long-Term Serum Platinum Concentrations on Neuro- and Ototoxicity in Cisplatin-Treated Survivors of Testicular Cancer

Cisplatin-induced neurotoxicity and ototoxicity (NTX) are important adverse effects after chemotherapy for testicular cancer (TC). Although serum platinum is measurable years after therapy, its impact on NTX has not been evaluated. In all, 169 cisplatin-treated survivors of TC provided blood samples...

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Veröffentlicht in:	Journal of clinical oncology 2012-01, Vol.30 (3), p.300-307
Hauptverfasser:	SPRAUTEN, Mette, DARRAH, Thomas H, TRAVIS, Lois B, PETERSON, Derick R, ELLEN CAMPBELL, M, HANNIGAN, Robyn E, CVANCAROVA, Milada, BEARD, Clair, HAUGNES, Hege S, FOSSA, Sophie D, OLDENBURG, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Cisplatin - administration & dosage Cisplatin - adverse effects Cisplatin - blood Cochlea - drug effects Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Middle Aged Neurotoxicity Syndromes - blood Neurotoxicity Syndromes - etiology Original Reports Platinum - blood Surveys and Questionnaires Survival Analysis Survivors Testicular Neoplasms - blood Testicular Neoplasms - drug therapy Tumors Tympanic Membrane - drug effects Young Adult
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