Peripheral chondrosarcoma progression is associated with increased type X collagen and vascularisation

Endochondral bone formation requires a cartilage template, known as the growth plate, and vascular invasion, bringing osteoblasts and osteoclasts. Endochondral chondrocytes undergo sequences of cell division, matrix secretion, cell hypertrophy, apoptosis, and matrix calcification/mineralisation. In...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2012-01, Vol.460 (1), p.95-102
Hauptverfasser:	de Andrea, Carlos E., Wiweger, Malgorzata I., Bovée, Judith V. M. G., Romeo, Salvatore, Hogendoorn, Pancras C. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Apoptosis Biological and medical sciences Bone Neoplasms - metabolism Bone Neoplasms - pathology Cell Differentiation Child Child, Preschool Chondrocytes - pathology Chondrosarcoma - metabolism Chondrosarcoma - pathology Collagen Type X - metabolism Disease Progression Diseases of the osteoarticular system Female Growth Plate - metabolism Growth Plate - pathology Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Medicine Medicine & Public Health Middle Aged Mineralization Mutation Mutation - genetics N-Acetylglucosaminyltransferases - genetics Neovascularization, Pathologic - pathology Original Original Article Ossification, Heterotopic - pathology Osteochondroma - metabolism Osteochondroma - pathology Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Retrospective Studies Tumors of striated muscle and skeleton Young Adult
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